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Published Research Copper Binding and Skin-Regeneration Signaling Pickart, Vasquez-Soltero, and Margolina (2015) reviewed GHK and GHK-Cu as modulators of multiple cellular pathways, summarizing in vitro and preclinical data on the peptides copper-binding behavior and its associations with collagen synthesis, antioxidant activity, and anti-inflammatory signaling in skin-cell models [1]

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