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(3) Publications reporting mechanistic insights (e.g., cell death pathways, inflammatory signaling) or therapeutic interventions

When food stays in your stomach longer, it sits in contact with stomach acid for extended periods, increasing the chance acid backs up into your esophagus, causing that burning sensation

Unlike the pro-inflammatory properties of leptin, adiponectin exerts its anti-inflammatory effects by inhibiting macrophage phagocytosis and TNF- production, and its secretion may be reduced by adipocyte hypertrophy and dysfunction of adipose tissue (155, 156)